In the world of advanced aesthetics, few ingredients have generated as much excitement as polynucleotides (PDRN) — derived from purified Salmon DNA. Once reserved for in-clinic injectable treatments, this regenerative biotechnology is now transforming topical skincare.

At Rodial, we’ve taken this clinical breakthrough and reimagined it as a luxurious, clean, high-performance collection designed for visible renewal — without needles, downtime or inflammation 

What Is Salmon DNA (PDRN) in Skincare?

Polynucleotides (PDRN) are highly purified DNA fragments derived from salmon. They are considered exceptionally biocompatible with human skin, meaning they work in harmony with your skin’s natural repair processes while minimising the risk of irritation.

In aesthetic medicine, injectable polynucleotides have become a gold-standard treatment for:

• Repairing thinning or ageing skin

• Stimulating collagen production

• Improving elasticity and firmness

• Enhancing skin density and texture

• Supporting recovery from stress and environmental damage

This science formed the foundation of Rodial’s most advanced clean formulation to date.

From Clinical Injection to Daily Skincare Ritual

Inspired by these regenerative treatments, Rodial developed Salmon DNA Water Oil — a first-of-its-kind bi-phase formula from a Western brand.

After two years of formulation and 42 iterations, the result is a sophisticated water-oil system containing an exceptional 59% active ingredient

Why the Dual-Phase Technology Matters

The innovative two-phase delivery system mirrors professional treatment methods:

• Water phase: Delivers Polynucleotides (PDRN), Growth Factors and NAD+ to support collagen synthesis, boost cellular energy and enhance firmness

• Oil phase: Reinforces the skin’s lipid barrier with fatty-acid-rich botanical oils to lock in hydration and prevent moisture loss

Together, these phases work synergistically to restore radiance, improve elasticity and strengthen the complexion.

The Power Trio: Polynucleotides, NAD+ and Growth Factors

The Salmon DNA range is powered by three clinically inspired actives:

1. Polynucleotides (PDRN)

Support skin repair and regeneration, helping reduce visible signs of ageing

2. RejuveNAD™ (NAD+)

Reactivates cellular energy to improve skin longevity and restore a fresher, more youthful appearance

3. Growth Factors (EGF / Epitensive™)

Stimulate collagen, elastin and hyaluronic acid production for visibly firmer, smoother skin

Visible Results, Without Downtime

Salmon DNA Water Oil offers offers non-invasive, inflammation-free alternative for daily use

Clinical-inspired testing shows:

• Skin appears up to 10 years younger

• 98% reduction in wrinkle depth in 8 weeks

• 95% increase in collagen production

Extending the Regeneration: The Full Salmon DNA Collection

The range also includes:

Salmon DNA Hydrogel Face Mask

A single-treatment rejuvenation mask combining Salmon DNA, NMN (a precursor to NAD+) and multi-weight hyaluronic acid for deep hydration and visible renewal

Salmon DNA Jelly Eye Patches

Cooling hydrogel patches infused with Salmon DNA, Growth Factors and Exosomes to brighten, smooth and revitalise tired under-eyes

Clean, Conscious Biotechnology

The Salmon DNA range marks a new era for Rodial — clinically driven and clean-conscious, developed with no compromise

The formulas are:

• Paraben-free

• Phthalate-free

• SLS/SLES-free

• Alcohol-free

• Cruelty-free

• Free from mineral oil, petrochemicals and microplastics

With 98.9% natural-origin ingredients in the Water Oil, this is high-performance skincare aligned with modern clean standards

The Future of Regenerative Skincare

Salmon DNA skincare represents the evolution of beauty: clinically inspired, biotechnology-powered, and designed for daily transformation.

What was once an injectable-only aesthetic innovation is now bottled into a luxurious ritual — delivering collagen support, cellular energy and barrier repair in one advanced formula.

This is regenerative skincare redefined.